Mutagenicity of CORAGRAF and REKAGRAF in the Ames test.
- Author:
Suzina AH
;
Azlina A
;
Shamsuria O
;
Samsudin AR
- Publication Type:Journal Article
- MeSH:
Base Pair Mismatch/drug effects;
Biotransformation/physiology;
Bone Substitutes/*toxicity;
Calcium Carbonate/*toxicity;
Chromosome Aberrations;
Escherichia coli/genetics;
Hydroxyapatites/*toxicity;
*Materials Testing;
*Mutagenicity Tests;
Salmonella typhimurium/genetics
- From:
The Medical Journal of Malaysia
2004;59 Suppl B():105-106
- CountryMalaysia
- Language:Malay
-
Abstract:
Mutagenicity of CORAGRAF (natural coral) and REKAGRAF (hydroxyapatite) was tested in Ames test with and without an external metabolic activation system (S9). The test revealed no mutagenic activity of both locally produced osseous substitutes.