Biocompatibility test of polyhydroxybutyrate on human cell line.
- Author:
Raouf AA
;
Samsudin AR
;
Al-Joudi FS
;
Shamsuria O
- Publication Type:Journal Article
- MeSH:
Cell Line;
Cell Survival/*drug effects;
Fibroblasts/drug effects;
Hydroxybutyrates/*toxicity;
*Materials Testing;
Polymers/*toxicity
- From:
The Medical Journal of Malaysia
2004;59 Suppl B():101-102
- CountryMalaysia
- Language:Malay
-
Abstract:
The human fibroblast MRC-5 cells incubated with PHB granules (TM) added at a final concentration of 4 mg/ml showed a time-course pattern of survival. The percentages of dead cells obtained were at the rate of 3.8% after 7 days, respectively. When the MRC-5 cells grown in different material, using the test concentration of 4 mg/ml PCM, they were found to show a similar time-course increasing pattern of death as that obtained with PHB. However, the death was noted in the cells incubated for 7 days, the death rates obtained was 40.54% respectively.
