Interferon induced glomerular disease in a patient with chronic hepatitis C.
- Author:
Suresh RL
;
Suryati Y
;
Merican I
- Publication Type:Case Reports
- MeSH:
Antiviral Agents/*adverse effects;
Drug Therapy, Combination;
Hepatitis C, Chronic/*drug therapy;
Interferons/*adverse effects;
Liver Function Tests;
Nephrotic Syndrome/*chemically induced;
Ribavirin/administration & dosage
- From:
The Medical Journal of Malaysia
2003;58(4):594-596
- CountryMalaysia
- Language:Malay
-
Abstract:
Chronic hepatitis C manifests with many extrahepatic features including renal involvement. However, less commonly, interferon therapy for chronic hepatitis C can also result in renal involvement and we describe a case when interferon therapy resulted in minimal change glomerulopathy, a form of involvement which, carries a good prognosis. Our patient developed nephrotic syndrome while on interferon therapy and HCV RNA levels were undetectable at that time. The disease showed excellent response to steroid therapy.