Anti N-Methyl-D-Aspartate Receptor Encephalitis with Ovarian Teratoma: A Dilemma in Diagnosis
- Author:
Lee CL
;
Zainuddin AA
;
Abdul Karim AK
;
Yulianty A
;
Law ZK
;
Md.Isa N
;
Nor Azlin MI
- Publication Type:Case Reports
- Keywords:
Anti-N-Methyl-D-Aspartate receptor;
encephalitis;
ovarian tumour;
psychosis;
teratoma
- MeSH:
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
- From:Journal of Surgical Academia
2016;6(1):66-69
- CountryMalaysia
- Language:English
-
Abstract:
We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old
woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation
revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result
showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-DAspartic
acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody
associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the
tumour and immunotherapy resulted in full recovery.
- Full text:P020160607533286458271.pdf
