The Hidden Salmon Patch: Ocular Lymphoma Mistaken as Vogt Koyanagi Disease
- Author:
Nazima SA
;
Muhaya M
;
Kok HS
;
Hazlita MI
- Publication Type:Case Reports
- Keywords:
intraocular lymphoma;
MALT lymphoma;
orbital neoplasms;
uveitis;
Vogt Koyanagi Harada disease
- MeSH:
Uveomeningoencephalitic Syndrome
- From:Journal of Surgical Academia
2016;6(1):46-50
- CountryMalaysia
- Language:English
-
Abstract:
Ocular inflammation from various causes may have similar clinical presentation thus careful clinical evaluations are
mandatory particularly when the disease appear to be resistant to treatment. This paper reports a case of ocular
lymphoma which was initially treated as Vogt Koyanagi Harada disease at a different centre. A 65-year-old
Sudanese man complained of gradual worsening left eye vision. Careful ocular and slit lamp examination revealed a
conjunctival lesion with choroidal infiltration as well as exudative retinal detachment. Computed tomography scan
(CT scan) showed left eye axial proptosis, and a homogenous enhancing mass at the posterior coat of the globe.
Tissue biopsy of the conjunctival lesion revealed marginal Zone B cell (MALT type), low grade, non-Hodgkin’s
lymphoma. AS the ocular signs and symptoms progressed, chemotherapy was initiated. The proptosis, exudative
retinal detachment, disc hyperemia and swelling improved after chemotherapy. The post treatment CT scan showed
reduction of the posterior ocular coat mass. The possibility of malignant lymphoma should be considered in patients
with resistant uveitis despite administration of corticosteroid. Ocular lymphoma is an indolent tumour with good
prognosis. Careful ocular examination, adequate imaging studies followed by early surgical biopsy will contribute to
early diagnosis.
- Full text:P020160607477659110741.pdf
