Oily fish, liquid wax esters and keriorrhoea – a review
- Author:
Peter Michael Barling
;
Yi Huan Foong
- Publication Type:Review
- Keywords:
keriorrhoea;
liquid wax esters;
orange roughy;
escolar;
oilfish;
lipase;
2-monoglyceride
- MeSH:
Lipase
- From:International e-Journal of Science, Medicine and Education
2015;9(1):21-25
- CountryMalaysia
- Language:English
-
Abstract:
Keriorrhoea is the involuntarily passing
of orange oil per rectum. One of us (PMB) had the
misfortune to experience this symptom, together
with considerable gastrointestinal disturbances for a
prolonged period of time after consumption of a deep
sea fish, orange roughy, which is rich in liquid wax esters
(LWEs). This paper presents a summary of available
evidence concerned with the physiology and pathology
of ingestion of LWEs, which can enter the human diet in
substantial amounts from consumption of several species
of deep-sea fish. LWEs are poorly digested and absorbed
by the human body. They generally cause keriorrhoea
when ingested deliberately or accidentally. Jojoba oil,
which is a plant LWE, together with certain nutritional
products (e.g. olestra) and medical (e.g. Orlistat) which
are not LWEs may mimic the effects of LWEs, and
cause similar gastrointestinal disturbances. This paper
discusses the potential effects of LWEs as components of
gastrointestinal micelles, and predicts that the orange oil
which is leaked from a bout of keriorrhoea may contain
considerable volumes of triacylglycerols (TAGs).
- Full text:P020150526323749511539.pdf
