Uncomplicated hyperemesis gravidarum does not alter the course of cardiovascular changes during pregnancy
- Author:
Sheila Rani Kovil George
;
Sivalingam Nalliah
- Publication Type:Journal Article
- Keywords:
Normal pregnancy;
cardiac changes;
echocardiogram;
uncomplicated hyperemesis gravidarum
- MeSH:
Pregnant Women;
Pregnancy
- From:International e-Journal of Science, Medicine and Education
2014;8(1):34-43
- CountryMalaysia
- Language:English
-
Abstract:
The purpose of this prospective longitudinal
study was to investigate the maternal cardiac
haemodynamic and structural changes that occur
in pregnancies with uncomplicated hyperemesis
gravidarum in a selected Malaysian population. Nine
women underwent serial echocardiography beginning
at 12 weeks of gestation and throughout pregnancy
at monthly intervals. Their echocardiograms were
repeated at 6 and 12 weeks following delivery to reflect
the pre-pregnancy haemodynamic state. Cardiac output
was measured by continuous wave Doppler at the aortic
valve. Interventricular septum thickness was determined
by M- mode echocardiography and ventricular diastolic
function by assessing flow at the mitral valve with
Doppler recording. Cardiac output showed an increase
of 32.9% at 36 weeks and maintained till 40 weeks of
gestation. Heart rate increased from 79 ± 6 to 96 ± 8 beats/
min at 36 weeks. Stroke volume increased by 16.4 % at
40 weeks of gestation when compared to the baseline
value. Systolic and diastolic blood pressure did not
appreciably change but showed a lower reading during
the mid-trimester period. Early inflow velocity of left
ventricle did not show a rise while peak atrial velocity
showed an increasing trend; thus the ratio of early inflow
to peak atrial transport showed a declining trend from
early pregnancy to term. End diastolic dimension of left
ventricle and interventricular septum thickness showed
an increased value at term. Uncomplicated hyperemesis
gravidarum did not alter the haemodynamic changes
throughout pregnancy and concur with established data
for normal pregnancy.
- Full text:P020150528362699056939.pdf
