Extra-gonadal Germ Cell Tumour – What About the Testis!
- Author:
Johann FK
;
Praveen S
;
Christopher CKH
;
Goh EH
;
Razman J
;
Zulkifli MZ.
- Publication Type:Case Reports
- Keywords:
Extragonadal, germ cell tumour, testis, factors, histopathology, treatment
- From:Journal of Surgical Academia
2011;1(1):28-31
- CountryMalaysia
- Language:English
-
Abstract:
Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature as in a majority of them, a primary source is found in the testis, thus representing a metastatic gonadal tumour. The testis pathology could be either a true germ cell foci, an intra-tubular epithelial neoplasia or an area of fibrosis, indicating a ‘burnt out tumour’. We report a 39-year-old male who underwent laparotomy and excision of a retroperitoneal tumour. Histopathological examination revealed retroperitoneal lymph node of mixed germ cell tumour origin. Clinical and ultrasound examination of bilateral testis was normal. The patient refused orchidectomy or a testicular biopsy. He underwent four cycles of bleomycin, cisplatin, and etoposide with no evidence of tumour recurrence on follow up and remains disease free after 12 months of diagnosis. A literature review of EGGCT, its relation and factors relating with future testicular tumour is presented.
- Full text:W020151005562725117093.pdf
