Reversible splenial lesion syndrome caused by rubella infection
- Author:
Pahn Kyu Choi
;
Eun Ju Yoon
;
Sang Woo Ha
;
Hyun Goo Kang
- Publication Type:Case report
- Keywords:
Corpus callosum;
reversible splenial lesion syndrome;
rubella
- MeSH:
Rubella
- From:Neurology Asia
2017;22(3):271-274
- CountryMalaysia
- Language:English
-
Abstract:
Reversible splenial lesion syndrome can be caused by viral infection. Rubella generally occurs in
childhood, and it is rarely accompanied by neurological complications in adulthood. A 35-year-old man
visited our hospital due to conjunctival injection, mild fever, and headache 3 days after experiencing
skin rash. Brain magnetic resonance imaging (MRI) revealed distinct lesions involving white matter in
the splenium of the corpus callosum approximately 3 days following the onset of symptoms. Enzyme
immunoassay performed on serum and CSF samples was positive for rubella virus IgM. A follow-up
brain MRI was performed 24 days after the onset of symptoms, and reduced lesion size with decreased
signals were observed on diffusion weighted image. This case showed that rubella infection can result
in reversible splenial lesion accompanied by only mild neurological symptoms.
