The impact of pain, anxiety and depression on sleep quality in Chinese patients with neuromyelitis optica spectrum disorders
- Author:
Xiaohui Miao
;
Ziyan Shi
;
Hongxi Chen
;
Hongyu Zhou
;
Rong Yang
- Publication Type:Original article
- Keywords:
Neuromyelitis optica spectrum disorders;
pain;
anxiety;
depression;
disability;
sleep quality
- MeSH:
Neuromyelitis Optica
- From:Neurology Asia
2017;22(3):235-241
- CountryMalaysia
- Language:English
-
Abstract:
Background & Objective: Sleep quality in neuromyelitis optica spectrum disorders (NMOSD) were
investigated in two recent studies. However, factors affecting sleep quality have not been studied in
NMOSD. This study aimed to investigate the prevalence of sleep disorders in Chinese outpatient clinics
with NMOSD and its clinical correlates. Methods: We administered Chinese validated self-questionnaires
on HRQOL (MSQOL-54), sleep (PSQI), pain (SF-MPQ-2), anxiety (HARS) and depression (HDRS)
to 42 patients followed up in our outpatient department. We assessed the relationships between sleep
quality with pain, anxiety, depression, gender, age, disability, disease duration, NMO-antibody status
and explored the determinants of poor sleep quality. Results: Sixty four percent of NMOSD patients
were poor sleepers. Significant correlations were found between duration, disability, pain, anxiety,
depression and sleep quality. Disability, depression and the domain of affective descriptors of pain
were the three main predictors of poor sleep in NMOSD.
Conclusion: This study reveals that poor sleep in NMOSD is common and it decreases physical function
of quality of life. It is worthwhile considering exploring adjuvant strategies aimed at controlling pain
associated affect, and treatment of depression may help to improve sleep quality in NMOSD.
