Clinical characteristics of febrile seizures and risk factors of its recurrence in Chiang Mai University Hospital
- Author:
Worawit Kantamalee
;
Kamornwan Katanyuwong
;
Orawan Louthrenoo
- Publication Type:Original asticle
- Keywords:
Febrile seizure;
simple febrile seizure;
complex febrile seizure;
recurrent febrile seizure;
epilepsy
- MeSH:
Seizures, Febrile
- From:Neurology Asia
2017;22(3):203-208
- CountryMalaysia
- Language:English
-
Abstract:
Background & Objectives: Febrile seizures are the most common convulsive disorder in children
under 5 years old. Among these children, some develop recurrent febrile seizures. The objective of
this study was to describe clinical characteristics of children with febrile seizures and to identify risk
factors for developing recurrent seizures. Methods: A retrospective study was conducted from January
2004 to December 2013 in Chiang Mai University Hospital. Infants and children between 6 months
and 5 years of age who were diagnosed with febrile seizures were included in this study. Clinical
characteristics of children and all factors associated with seizure recurrence were extensively reviewed
using electronic medical records. Results: There were 335 cases included for analysis. The mean
age at onset of febrile seizures was 1.85 ± 0.95 years; 64.78 % were males. Among 261 cases who
presented with first episode of febrile seizures, 52 cases (19.92%) developed recurrent febrile seizures.
Respiratory tract infections were the most frequent etiology of febrile illnesses. Younger age at onset
and family history of febrile seizures were statistically significant predictors of developing recurrent
febrile seizures (p = <0.001 and 0.02, respectively). After adjusting the confounding variables, similar
findings were found from the multiple logistic regression analysis (p = 0.003 and 0.01 respectively).
Conclusion: In this study, younger age at onset of first febrile seizure and family history of febrile
seizures were found to increase the risk of the recurrence of febrile seizures.
