The pathogenic mechanisms of motor weakness following aneurysmal subarachnoid hemorrhage: A review
- Author:
Sung Ho Jang
;
Han Do Lee
- Publication Type:Review article
- Keywords:
Subarachnoid haemorrhage;
aneurys;
motor weakness;
hemiplegia;
paraplegia;
quadriparesis
- MeSH:
Subarachnoid Hemorrhage
- From:Neurology Asia
2017;22(3):185-191
- CountryMalaysia
- Language:English
-
Abstract:
Motor weakness is one of the neurological complication that can occur after aneurysmal subarachnoid
hemorrhage (SAH); incidence of motor weakness of 14~29% has been reported. Detailed information
on the pathogenic mechanism of motor weakness is essential for brain rehabilitation because it enables
estimation of the severity of injury, establishment of scientific rehabilitative strategies, and prediction
of motor outcomes by clinicians. However, the exact pathogenic mechanisms of motor weakness
following aneurysmal SAH have not been clearly elucidated. In this article, 14 previous studies on
pathogenic mechanisms in patients with aneurysmal SAH were reviewed according to the location of
the lesion (cerebral cortex, brainstem, spinal cord, and peripheral nerve). The following pathogenic
mechanisms have been suggested: vasospasm, cerebral ischemia, hydrocephalus, compression of
cerebral cortex, neural injury, spinal cord infarction, and radiculo-neuropathy. Considering the high
incidence of aneurysmal SAH and motor weakness following aneurysmal SAH, we believe that the
pathogenic mechanisms of motor weakness have been relatively understudied. More effort should be
taken to investigate this important topic.
