H1N1 induced ards: ecmo as rescue therapy in patients with failed mechanical ventilation – a review
- Author:
Ismail AH
;
Marzida M
;
Kumar NM
;
Ong Gracie SY
- Publication Type:Journal Article
- Keywords:
Influenza;
H1N1;
ARDS;
ECMO
- MeSH:
Influenza, Human
- From:Journal of University of Malaya Medical Centre
2010;13(2):80-87
- CountryMalaysia
- Language:English
-
Abstract:
Since the outbreak of the novel influenza H1N1 in Mexico in April 2009, more than half a million
cases have been recorded with close to 6000 deaths. In contrast to seasonal flu, this virus
appears to have a predilection for the young, obese and pregnant. It’s most important and
almost fatal complication is Acute Respiratory Distress Syndrome (ARDS). ICUs around the world
have scrambled to upgrade various treatment modalities including high frequency oscillation
ventilation, inotropes, antivirals and antibiotics in an effort to reduce the mortality arising out of
this complication. More importantly, this complication appears reversible if adequate and early
therapy is instituted. In particular, rescue therapies that allow the lung to rest appear to have
brought success in some clinical settings. This article describes the experiences of six centres that
have used Extracorporeal Membrane Oxygenation (ECMO) as rescue therapy in patients having
ARDS. ECMO has been instituted in many of these cases not only as a bridge to therapy but also
to reduce further barotrauma in these patients. ECMO experiences regarding 2 patients at the
University of Michigan, 7 in Canada, 68 patients at Leicester UK, 68 in Australia and New Zealand,
1 in Hong Kong and 2 in Singapore are described. (JUMMEC 2010; 13(2): 80-87)
- Full text:P020160120414817465555.pdf
