The Rare Primary Low Grade Papillary Adenocarcinoma of Nasopharynx: A Diagnostic Challenge and Management
- Author:
Noor Dina H
;
Gendeh BS
- Publication Type:Case Reports
- Keywords:
adenocarcinoma papillary;
nasopharynx;
thyroid neoplasms
- MeSH:
Thyroid Neoplasms
- From:Medicine and Health
2015;10(2):137-140
- CountryMalaysia
- Language:English
-
Abstract:
Low Grade Papillary Nasopharyngeal Adenocarcinoma (LGPAC) is a very rare
tumour of mucosal origin compared to a higher incidence of well differentiated
keratinized/non-keratinized nasopharyngeal carcinoma. It is an epithelial tumour
with glandular differentiation. Its papillary figure seen histologically, is also seen in
metastatic papillary thyroid carcinoma. This has caused a significant challenge to
the Pathologist to differentiate primary papillary nasopharyngeal adenocarcinoma
and metastatic tumour. Thyroid Transcription Factor-1 (TTF-1) is also expressed
in subsets of papillary nasopharyngeal adenocarcinoma, which is valuable as a
diagnostic tool. LGPAC is a benign-like malignant neoplasm. An early diagnosis
with a complete tumour removal via conventional excision or endoscopic approach
has offered a good prognosis with low risk of recurrence.
- Full text:P020151118530913971443.pdf
