Neuro-Behçet’s disease mimicking cerebral abscesscomplicated by metronidazole-induced encephalopathy
- Author:
Ayse Guler
;
Ece Cinar
;
Tuncer Turhan
;
Husnu Pullukcu
;
Taner Akalin
;
Figen Gokcay
;
Nese Celebisoy
- Publication Type:Case Reports
- MeSH:
Dizziness
- From:Neurology Asia
2015;20(3):291-295
- CountryMalaysia
- Language:English
-
Abstract:
This is the report of a 32-year-old man with Behçet’s disease described dizziness, double vision and
headache. The cranial MRI demonstrated a ring enhancing nodular lesion in left medial occipital lobe,
and T2 hyperintense lesion in diencephalon mimicking abscesses. A stereotactic biopsy was performed.
The histology showed features of neuro-Behçet’s disease and an abscess was ruled out. During the
procedure till the histopathologic results were gathered he was given ceftriaxone and metronidazole
when cerebellar signs appeared. Cranial MRI showed additional symmetrical hyperintensities in bilateral
cerebellar dentate nuclei which was attributed to metronidazole toxicity. Repeat MRI performed forty
days later showed complete resolution of both dentate hyperintensities and diencephalic and occipital
ring enhancing lesions. This is the first case of neuro-Behcet’s disease complicated by metronidazoleinduced
encephalopathy. This case also showed that nodular ring enhancing lesions can be seen in
neuro-Behçet’s disease and can lead to difficulties in diagnosis and management.
- Full text:P020151007471307922764.pdf
