The role of psychological resilience, severity of disease and treatment adherence in the prediction of health-related quality of life in patients with multiple sclerosis
- Author:
Habib Hadianfard
;
Nahid Ashjazadeh
;
Soodabe Feridoni
;
Elham Farjam
- Publication Type:Journal Article
- MeSH:
Multiple Sclerosis;
Quality of Life
- From:Neurology Asia
2015;20(3):263-268
- CountryMalaysia
- Language:English
-
Abstract:
Objective: This cross-sectional study aims to evaluate the impact of the disability status, psychological
resilience, and treatment adherence on health-related quality of life (QOL) in patients with multiple
sclerosis (MS). Methods: One hundred MS outpatients, 80 women and 20 men, referred to a clinic
of Shiraz University of Medical Sciences, were eligible to participate. MS was diagnosed by 2010
revised Mc-Donald criteria. The QOL and resilience were evaluated by the Medical Outcomes Study
Short-Form (SF-36) and Connor-Davidson Resilience Scale (CD-RISC) respectively. Medication
adherence and severity of disease were assessed by the Morisky Medication Adherence Scale (MMAS)
and expanded disability status state (EDSS) scores respectively. Results: Stepwise multiple regressions
showed that in the first model, the disability status was the best predictor which accounted for 28.1%
of the variance in QOL. In the second model, both the disability status and resilience explained 50.6%
of the variation in QOL.
Conclusion: The findings showed that the severity of the disease is a strong predictor which has
adverse effects on the physical component of health-related QOL in the patients with MS. Both
psychological resilience and treatment adherence have positive influence on mental component of
QOL in these patients.
- Full text:P020151007457112147523.pdf
