Association of hypothyroidism in patients with migraine and tension-type headache disorders in Kashmir, North India
- Author:
Hamed B Khan
;
Parvaiz A Shah
;
M Hayat Bhat
;
Ali Imran
- Publication Type:Journal Article
- MeSH:
Headache Disorders;
Hypothyroidism;
Migraine Disorders
- From:Neurology Asia
2015;20(3):257-261
- CountryMalaysia
- Language:English
-
Abstract:
Objective: This case control study was undertaken to ascertain the frequency of subclinical and overt
hypothyroidism in patients with various types of primary headache disorders in Kashmir, North India.
Methods: The study was conducted in a tertiary care (university of Kashmir) hospital of North India.
The study subjects consisted of 250 patients with primary headache disorders. This was compared
with an age-sex matched control of 500 subjects. Thyroid function tests were performed by new
automated immunochemiluminometric assay. Results: Among patients with primary headache disorders,
subclinical hypothyroidism was present in 22% and overt hypothyroidism in 7.2%. On the other hand,
subclinical hypothyroidism was observed in 11.2% and overt hypothyroidism in 1.2% of cases in the
control group, the differences between primary headache and control group was statistically significant
(p<0.05). Frequency of hypothyroidism was more in chronic headache disorders (chronic tension-type
headache and migraine). The frequency of hypothyroidism in patients with primary headache disorders
was higher among females than males, but this was not statistically significant (p> 0.05).
Conclusion: Hypothyroidism is found to be a co-morbidity or predisposes to the development of
chronic headache (tension-type headache and migraine) in this North Indian study.
- Full text:P020151007455027618912.pdf
