Multiple sclerosis in South East Asia and diagnostic criteria for Asians
- Author:
HT Chong
- Publication Type:Case Reports
- From:Neurology Asia
2008;13(1):145-146
- CountryMalaysia
- Language:English
-
Abstract:
Multiple sclerosis is an uncommon disease in Southeast Asia, having been characterised only recently.
The estimated prevalence is about 2 – 3/105
, with high female to male ratio, but rare family history.
As high as 40% of the patients had the optic-spinal phenotype; though patients in this region seldom
progressed to the secondary progressive phase, disability was more severe due to severe spinal cord
involvement. There is a great degree of overlap in clinical, radiological and laboratory features between
the classical and the optic-spinal phenotypes, including long spinal cord involvement, few brain lesions,
lower proportion of positive cerebrospinal fluid oligoclonal bands and anti-aquaporin-4 antibody. We
proposed that future international diagnostic criteria need to take this into account.
- Full text:P020150901430481768137.pdf
