Antiepileptic drug trials with greater attention to daily clinical practice and special epilepsy syndromes
- Author:
Wei-Ping Liao
- Publication Type:Journal Article
- From:Neurology Asia
2007;12(Supplement 1):30-32
- CountryMalaysia
- Language:English
-
Abstract:
Most of the present antiepileptic drug trials focus on efficacy and short-term safety with limited
information relevant for daily clinical practice, such as spectrum of efficacy, effective dose, titration
method, drug interactions, and long-term outcome. Antiepileptic drug trials more akin to daily clinical
practice should also be emphasized in future trials. There are, limited randomized control trials for
certain seizure types or epilepsy syndromes, such as Lennox-Gastaut syndrome and severe myoclonic
epilepsy in infancy. The author proposed self-controlled “class S” study in patients who has well-defined
epilepsy syndrome with homogeneity in evolution of illness and high frequency of seizures.
- Full text:P020150828424750515205.pdf
