Defining drug-resistant epilepsy
- Author:
Patrick Kwan
- Publication Type:Journal Article
- From:Neurology Asia
2011;16(Supplement 1):67-69
- CountryMalaysia
- Language:English
-
Abstract:
Drug resistant epilepsy remains a major clinical challenge. Diverse criteria have been used to defi ne
drug resistance by different researchers, making it diffi cult or even impossible to compare the results
across different studies. To improve patient care and facilitate clinical research, the International League
Against Epilepsy recently proposed a consensus defi nition to defi ne drug resistant epilepsy as failure of
adequate trials of two tolerated, appropriately chosen and used antiepileptic drug schedules (whether
as monotherapies or in combination) to achieve sustained seizure freedom. This article outlines the
framework of the consensus defi nition, explains how to apply it in practice, and discusses the future
development in its use.
- Full text:P020150824415223321223.pdf