Effectiveness of transsylvian selective amygdalohippocampectomy for preserving memory function in patients with hippocampal sclerosis
- Author:
Michiharu Morino
;
Takehiro Uda
;
Taiki Nagai
;
Noriaki Minami
;
Hirotaka Ito
;
Atsushi Hosono
- Publication Type:Journal Article
- From:Neurology Asia
2013;18(s1):51-55
- CountryMalaysia
- Language:English
-
Abstract:
It remains unclear whether selective amygdalohippocampectomy, an operative technique developed
for use in epilepsy surgery to spare unaffected brain tissue and thus minimize the cognitive
consequences of temporal lobe surgery, actually leads to a better memory outcome. The present
study was performed to investigate the effects of selective surgery on memory outcome in patients
with intractable mesial temporal lobe epilepsy due to hippocampal sclerosis treated by transsylvian
selective amygdalohippocampectomy (TSA). The results of the present study indicated that left
TSA for hippocampal sclerosis tends to improve verbal memory function with preservation of other
memory function. Right TSA for hippocampal sclerosis can lead to signifi cant improvement in verbal
and nonverbal memory function, with the memory improvement observed one month after right TSA
persisting until one year after surgery.
- Full text:P020150706607082826768.pdf
