Diffusion-weighted magnetic resonance imaging in a case of osmotic demyelination syndrome with fatal outcome
- Author:
Shen-Yang Lim
;
,Ismaliza Ismail
;
Sharon Mei-Ling Tai
;
Khairul Azmi Abdul Kadir
;
Li-Ping Tan
;
Yip-Boon Chong
;
Nortina Shahrizaila
- Publication Type:Case Reports
- From:Neurology Asia
2011;16(1):89-92
- CountryMalaysia
- Language:English
-
Abstract:
Hyponatraemia with rapid correction of serum sodium may cause an osmotic demyelination syndrome
(ODS) with damage to pontine and/or extrapontine areas of the brain. The prognosis of ODS can range
from complete recovery to death; at present, our ability to predict clinical outcome is very limited. We
describe here a patient with ODS and increased signal intensity in the striatum on diffusion-weighted
MRI, with corresponding low apparent diffusion coeffi cient values (indicating restricted water diffusion).
This case provides a further example of the typical MRI appearance of extrapontine ODS and suggests
the potential value of diffusion-weighted MRI in predicting prognosis in ODS.
- Full text:P020150731437918819349.pdf