Is hypothalamic involvement truly a red flag for multiple sclerosis?
- Author:
Chandra Mohan Sharma
;
Alok Jain
;
BL Kumawat
;
Dinesh Khandelwal
;
Deepak Jain
- Publication Type:Journal Article
- From:Neurology Asia
2013;18(3):323-325
- CountryMalaysia
- Language:English
-
Abstract:
Any hypothalamic disturbance manifesting clinically is considered a major red flag for multiple
sclerosis, whereas MRI lesions involving deep grey matter structures are considered an intermediate
red flag. However, hypothalamic lesions manifesting clinically with hypersomnia have been described
in some patients of multiple sclerosis. We report a case where the first and presenting feature of
multiple sclerosis was acute onset hypersomnia with bilateral hypothalamic lesions. On review of
recent literature, we also question whether clinical or radiological hypothalamic involvement is really
so unusual that it should be considered a red flag for multiple sclerosis
- Full text:P020150706572701269760.pdf
