Isolated bulbar palsy with anti-GM3 and GT1b antibodies
- Author:
Narongrit Kasemsap
;
Kannikar Kongbunkiat
;
Metha Apiwattanakul
;
Kittisak Sawanyawisuth
;
Somsak Tiamkao
- Publication Type:Journal Article
- From:Neurology Asia
2013;18(3):319-321
- CountryMalaysia
- Language:English
-
Abstract:
Isolated acute bulbar palsy has been described as one of the more rare variants of Guillain-Barré
syndrome. IgG anti-ganglioside antibodies are associated with axonal subtypes of Guillain-Barré
syndrome as well as Fisher syndrome. However, IgG against GM3 and GT1b in relation to bulbar
palsy is uncommon. In this case report, we describe a 64 year-old male patient presenting with
isolated bulbar weakness and generalized hyporeflexia without limb weakness. Serological testing
for antiganglioside antibodies was positive for IgG anti-GM3 and -GT1b, suggesting the association
of these antibodies with isolated bulbar palsy.
- Full text:P020150706570668140694.pdf