Moyamoya Disease in Asia
- Author:
Cong Han
;
Jie Chen
;
Shan Gao
;
Lian Duan
- Publication Type:Review
- From:Neurology Asia
2012;17(3):175-181
- CountryMalaysia
- Language:English
-
Abstract:
Moyamoya disease is a rare cerebrovascular disorder, characterised by progressive stenosis and/or
occlusion of the intracranial internal carotid artery and its proximal branches with the development
of a basal collateral network. Moyamoya disease has a high prevalence in Asia, particularly in Japan,
Korea and China. Ischemic events and intracranial bleeding are the most common clinical manifestation
of moyamoya disease. Although the benefi cial effect on hemorrhage is still not clear, revascularisation
surgery remains the most effective way to prevent the progression of ischemic symptoms. Moyamoya
disease has been investigated by numerous studies since it was fi rst described 50 years ago, many
conundrums remain to be solved. In this article, we review the history, epidemiology, aetiology, clinical
manifestation, diagnosis and treatment of moyamoya disease. Recent advances and future challenges
of moyamoya disease are also discussed.
- Full text:P020150710486489553665.pdf
