Association of serum uric acid level with ischemic stroke, stroke subtypes and clinical outcome
- Author:
Rajeshwar Koppula
;
Subash Kaul
;
A Venkateswar Rao
;
A Jyothy
;
Anjana Munshi
- Publication Type:Journal Article
- From:Neurology Asia
2013;18(4):349-353
- CountryMalaysia
- Language:English
-
Abstract:
Background and Objective: Uric acid is a neuroprotective agent. However, its relationship with
ischaemic stroke remains controversial. We analyzed the association between serum uric acid and
ischemic stroke and clinical outcome. Methods: The study subject consisted of 550 ischemic stroke
patients from the Nizam’s Institute of Health Sciences, Hyderabad, India with 550 matched healthy
controls. Serum uric acid levels were estimated, and follow-up interviews conducted with patients.
Results: There was a significant association of elevated levels of serum uric acid with stroke and its
subtypes except lacunar stroke. Patients with high serum uric acid levels had a significant increased
risk of poor outcome.
Conclusion: Serum uric acid level is associated with ischemic stroke, and is an independent prognostic
factor of poor outcome.
- Full text:P020150702577458876074.pdf
