Meningitis as early manifestation of anti-NMDAR encephalitis
- Author:
Sirichai Kittichanteera
;
Metha Apiwattanakul
- Publication Type:Journal Article
- From:Neurology Asia
2014;19(4):413-415
- CountryMalaysia
- Language:English
-
Abstract:
Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently discovered immune mediated
encephalitis. The syndrome typically occurs in children and young adult with initial presentations
of psychiatric symptoms, seizures, followed by abnormal movement and dysautonomia. There is
association with ovarian teratoma. We report here a 16-year-old girl with anti-NMDAR encephalitis,
who present with meningitis as initial symptom, confirmed by pleocytosis in the cerebrospinal fluid
and leptomeningeal enhancement in MRI. She subsequently manifested the more typical manifestations
of oro-facial dyskinesia and choreoathetosis. The diagnosis was confirmed by the presence of antiNMDAR
antibody. She was treated with immunotherapy with clinical improvement and drop in the
level of autoantibody. However the patient died due to septisemia.
- Full text:P020150701427411953458.pdf
