ADC evaluations of the hippocampus and amygdala in multiple sclerosis
- Author:
Mikail Inal
;
Birsen Unal Daphan
;
Yasemin Karadeniz Bilgili
;
Yakup Turkel
;
Ibrahim Kala
- Publication Type:Journal Article
- From:Neurology Asia
2014;19(4):387-391
- CountryMalaysia
- Language:English
-
Abstract:
Background & Objective:Diffusion-weighted MR imaging and apparent diffusion coefficient (ADC)
values provide significant structural information about tissues in multiple sclerosis (MS).The goal of
this study was to evaluate the ADC values in the hippocampus and amygdala in MS. Methods:Thirtyeightpatients
with MS and 41 healthy individualswere included in the study. ADC values were
measured bilaterallyfrom three different pointsin the hippocampus and amygdala in MS patients and
were compared with those of the controls. An analysis of varianceposthoc test was used to analyse the
differences among mean ADC values between MS and control groups.Results:The mean ADC values
of both sides of thehippocampus and the left amygdala in MS patients were lower than the control
group. The mean ADC values of the right amygdala in MS patients were lower than the control group,
but the difference was not statistically significant.
Conclusion:We observed restricted diffusion in the hippocampus and amygdala in MS patients contrary
to information in the literature.
- Full text:P020150701353183519094.pdf
