Prognostic value of routine haematological and biochemical parameters on 30 day fatality in patients with acute hypertensive intracerebral hemorrhage
- Author:
Durgesh Kumar Gupta
;
Virendra Atam
;
RK Garg
- Publication Type:Journal Article
- From:Neurology Asia
2012;17(1):13-20
- CountryMalaysia
- Language:English
-
Abstract:
Objective: This prospective study aimed to study the prognostic value of routine haematological
and biochemical parameters in patients of acute hypertensive intracerebral hemorrhage (ICH) on
fatality occurring during fi rst 30 days, and to estimate its case fatality rate, demographic and clinical
correlates. Methods: One hundred and eleven consecutive patients with proved hypertensive ICH
within 72 hours of symptom onset were studied. After clinical evaluation and neuroimaging, blood
investigations including hemoglobin, total leukocyte count, platelet count, erythrocyte sedimentation
rate, random blood sugar, urea, creatinine, sodium, potassium, serum bilirubin, aspartate transaminase
(AST), alanine transaminase (ALT), alkaline phosphatase (ALP), albumin estimations were performed.
The patients were followed up for a maximum period of 30 days from the onset of stroke. Results:
Logistic regression analysis demonstrated that a low Glasgow Coma Scale (GCS) score (Odd`s ratio
(OR) 17.54, p=0.001); high serum bilirubin (OR=7.97, p=0.021), and low serum albumin (OR=13.31,
p=0.001) correlated signifi cantly with death.
Conclusions: Our study shows that low GCS, raised serum bilirubin, and low serum albumin are
marker of poor outcome in ICH.
- Full text:P020150707444985172987.pdf
