Psychiatric morbidity in refractory mesial temporal lobe epilepsy before and after epilepsy surgery
- Author:
Sawant Neena S
;
Wankhede Shrikant S
- Publication Type:Journal Article
- MeSH:
Epilepsy, Temporal Lobe
- From:Neurology Asia
2015;20(2):129-138
- CountryMalaysia
- Language:English
-
Abstract:
Background & Objective: Psychiatric disorders constitute a large part of illness burden in patients with
refractory epilepsy. A careful presurgical psychiatric assessment is now an integral part of evaluation
in most centers performing surgeries for refractory epilepsy. This study was undertaken to determine
the prevalence of psychiatric disorders and outcome of the psychopathology in patients of refractory
mesial temporal lobe epilepsy (mTLE) before and after epilepsy surgery. Method: Forty eight patients
diagnosed as having refractory mTLE by the Neurologists were included in the study. The patients
were assessed using the Brief Psychiatric Rating Scale (BPRS), Beck’s Depression Inventory (BDI),
Hamilton Depression Rating Scale (HDRS) and Hamilton Anxiety Rating Scale (HARS) before
surgery as well as in the second and sixth month of postoperative period. Results: More than half of
the patients (54%) had psychopathology. Depressive disorders were more common. Lateralisation of
focus in MTS and psychopathology in the patient revealed equal right and left preponderance. No
significant difference was found on BPRS, BDI and HDRS scales at 2 and 6 months follow up post
epilepsy surgery in patients having psychopathology.
Conclusions: Patients had a favourable outcome after surgery as regards to their psychopathology as
well as the seizures.
- Full text:P020150707328901897468.pdf
