Atrial electrophysiological property analysis by sample entropy and atrial fibrillatory rate with cardiac autonomic derangements in acute ischemic stroke with atrial fibrillation
- Author:
Rattapong Sungnoon
;
Kesorn Suwanprasert
;
Sombat Muengtaweepongsa
- Publication Type:Journal Article
- From:Neurology Asia
2014;19(1):11-18
- CountryMalaysia
- Language:English
-
Abstract:
Background & Objective: Atrial fibrillation (AF) is the most common cardiac arrhythmia associated
with risk of ischemic stroke. Atrial electrophysiological properties are influenced by alteration of
cardiac autonomic tone. Cardiac autonomic derangement was reported in acute ischemic stroke
patients. Atrial activity analysis with sample entropy (SampEn) and atrial fibrillatory rate (AFR) are
the useful tools for evaluation of atrial electrophysiological properties. Heart rate variability (HRV)
is a good indicator for cardiac autonomic function. We aimed to evaluate atrial activity by SampEn
and AFR correlated with HRV in AF patients with acute ischemic stroke compared to which in AF
patients with previous ischemic stroke.
Methods and Results: Patients (age 69+10 years, n=40) were recruited, thereafter HRV, AFR, and
SampEn were analyzed from surface electrocardiogram (ECG). Acute stroke group showed significant
decreases in standard deviation of normal-to-normal intervals (SDNN), normalized low frequency
(LF) and high frequency (HF) power (138+36 ms vs. 170+61 ms, 13+4 vs. 18+8 and 34+8 vs. 46+15,
respectively) compared to post-stroke group. However, there was no significant difference in the LF
to HF power (LF/HF) ratio between these two groups (0.41+0.14 vs. 0.43+0.24). Moreover, SampEn
did not alter after stroke recovery, while AFR tended to decrease.
Conclusions: Atrial electrophysiology properties by SampEn and AFR are not influenced by cardiac
autonomic derangement during acute ischemic stroke period.
- Full text:P020150623453612115665.pdf
