Prevalence of Dyslipidaemia in Type 2 Diabetes Mellitus Patients and Its Association to Diabetic Retinopathy in a Malaysian Tertiary Hospital
- Author:
Intan Nureslyna Samsudin
;
Rafidah Md Saleh
;
Subashini C.Thambiah
;
Aiffa Syafira Mohamad Amir Hamzah
;
Wan Noor Fatini Wan Khalik
;
Elizabeth George
- Publication Type:Journal Article
- Keywords:
Diabetic retinopathy, Dyslipidaemia;
Non-proliferative diabetic retinopathy;
Proliferative diabetic retinopathy;
Type 2 diabetes mellitus
- MeSH:
Diabetic retinopathy
- From:Malaysian Journal of Medicine and Health Sciences
2014;10(2):47-51
- CountryMalaysia
- Language:English
-
Abstract:
Background: Diabetic retinopathy (DR) is a microvascular complication of diabetes, which is a cause of
visual impairment and blindness. Its development and progression have been linked to dyslipidaemia,
although the link remains inconclusive. Aim: This study aimed to determine the prevalence of
dyslipidaemia among type 2 diabetic patients with DR in a tertiary setting and to determine the association
between dyslipidaemia and DR severity. Materials and methods: This was a cross sectional study using
retrospective data of type 2 diabetic patients attending the opthalmology clinic of a tertiary centre from
January 2007 to June 2014. Results of their fasting lipid profile and clinical data were retrieved from
the hospital information system. Results: A total of 178 patient’s data were collected. 120 (n=67.4%)
patients had non-proliferative diabetic retinopathy (NDPR) with moderate NPDR being the most
prevalent. Dyslipidaemia was noted in 151 (84.8%) of the patients. Patients had a combination of more
than one abnormality in the lipid profile with increased LDL-cholesterol being the main abnormality.
Dyslipidaemia was however, not significantly associated with DR severity. Conclusion: Dyslipidaemia
was highly prevalent in DR patients. The dyslipidaemia was however not associated with severity of DR.
- Full text:P020150604525999190318.pdf
