Gastric Schwannoma in a Female Patient with Pulmonary Tuberculosis — A Clinicopathological Assessment and Diagnosis
- Author:
Tariq Mahmood Tahir
;
Sadia Anwar
;
Nadia Naseem
;
Hafiz Mansoor-Ul-Haq
;
Muhammad Saqib
- Publication Type:Case Reports
- Keywords:
gastrointestinal stromal tumours, immunohistocytochemistry, neurilemmoma, stomach, medical sciences
- From:Malaysian Journal of Medical Sciences
2010;17(2):45-50
- CountryMalaysia
- Language:English
-
Abstract:
Schwannomas, or neurinomas, are generally benign, slow-growing, asymptomatic neoplasms
originating from the Schwann cells of a nerve sheath. As a part of spindle cell mesenchymal tumours,
schwannomas arising from the gastrointestinal tract (GIT) are unusual; however, when they occur,
the most common site involved is the stomach, which represents 0.2% of all gastric tumours. We report
the case of a 35-year-old female patient with a history of pulmonary tuberculosis presenting with a
large palpable abdominal mass reaching up to the peritoneal cavity. The initial clinical impression
was a tuberculous abdominal mass, a cyst, or a teratoma. However, intra-operative findings during a
subtotal gastrectomy revealed an exophytic gastric serosal mass, which suggested a gastrointestinal
stromal tumour (GIST). Post-operative histopathological findings showed a fascicular arrangement
of neoplastic spindle cells with pallisading nuclei that showed intense positivity for S-100 protein,
and were negative for CD117 and desmin in immunohistochemistry studies. These results confirmed
the final diagnosis of a gastric schwannoma.
- Full text:W020151022430932227735.pdf
