Severe Episodic Memory Impairment in a Patient With Clinical Features Compatible With Corticobasal Degeneration.
- Author:
Sung Kwan KIM
1
;
Kyung Won PARK
;
Do Young KANG
;
Jae Kwan CHA
;
Sang Ho KIM
;
Jae Woo KIM
Author Information
- Publication Type:Case Report
- Keywords: Corticobasal degeneration; Episodic memory; PET
- MeSH: Apraxias; Executive Function; Humans; Memory; Memory Disorders; Memory, Episodic; Neurodegenerative Diseases; Neuropsychological Tests; Parkinsonian Disorders
- From:Journal of Clinical Neurology 2008;4(2):94-98
- CountryRepublic of Korea
- Language:English
- Abstract: Corticobasal degeneration (CBD) is a progressive neurodegenerative disorder characterized by asymmetric parkinsonism associated with apraxia, cortical sensory loss, and alien-limb phenomenon. Neuropsychological testing in patients with CBD typically shows deficits in executive functions, praxis, language, and visuospatial functioning, but not in memory. We report a CBD patient with severely impaired memory function but relatively mild motor symptoms. Detailed neuropsychological assessment showed significant verbal and visual memory deficits accompanied by frontal executive dysfunctions. Our observations indicate that CBD can in rare cases present with severe episodic memory impairment associated with frontal executive dysfunctions in the early stage of illness.
