Isolated Ipsilateral Nipple Recurrence: Important Lessons to Learn
- Author:
Shahrun Niza Abdullah Suhami
;
Rohaizak Muhammad
;
Ibrahim Naqiyah
;
Srijit Das
;
Noraidah Masir
- Publication Type:Case Reports
- Keywords:
breast-conserving surgery, diagnosis, nipple, recurrence, surgical oncology
- From:Malaysian Journal of Medical Sciences
2011;18(2):82-84
- CountryMalaysia
- Language:English
-
Abstract:
Most breast cancer recurrences occur in the surgical scars or within other quadrants of the
same breast. Isolated tumour recurrence occurring in the nipple after breast-conserving surgery
and radiotherapy is extremely unusual. The reason for this is unknown, but is speculated to be due to
involved surgical margins or an occult involvement of the nipple–areolar complex in a breast cancer
of the same breast. We present a case of a 44-year-old Indian woman who had recurrent tumour
over her right nipple after an ipsilateral breast-conserving surgery that was followed by adjuvant
chemotherapy and radiotherapy. There was no typical malignancy features from the mammogram.
However, histopathological study confirmed a malignant growth that infiltrated into the dermis and
the underneath breast tissue. Completion mastectomy was then performed and the patient was later
treated with Taxane-based chemotherapy. Nipple recurrence after breast-conserving surgery and
adjuvant radiotherapy may be confused with other nipple conditions such as Paget’s disease of the
breast. Comprehensive assessments, which include mammogram and biopsy, have proved that such
recurrence do occur, as presented in this case. This warrants a specific management strategy.
- Full text:W020151022577985348652.pdf