The Validity of Michigan Neuropathy Screening Instrument as a Screening Test and Risk Factors for Diabetic Peripheral Neuropathy.
- Author:
Hyun Young CHOI
1
;
Hyun Jin DO
;
Seung Won OH
;
Youl Lee LYM
;
Jae Kyung CHOI
;
Hee Gyung JOE
;
Hyuk Jung KWEON
;
Dong Yung CHO
Author Information
1. Department of Family Medicine, School of Medicine, Konkuk University, Seoul, Korea. cjk@kuh.ac.kr
- Publication Type:Original Article
- Keywords:
michigan neuropathy screening instrument;
diabetic neuropathy;
risk factor
- MeSH:
Amputation;
Blood Pressure;
Cholesterol;
Creatinine;
Diabetes Mellitus;
Diabetic Neuropathies;
Fasting;
Glucose;
Hemoglobin A, Glycosylated;
Humans;
Lipoproteins;
Mass Screening*;
Michigan*;
Peripheral Nervous System Diseases*;
Risk Factors*;
Sensitivity and Specificity;
Triglycerides;
Ulcer
- From:Journal of the Korean Academy of Family Medicine
2007;28(8):610-615
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Diabetic neuropathy is a common complication of diabetes. Since neuropathy leads to ulceration and amputation, efforts to detect early and to elucidate its risk factors are ongoing. The goal of this study was to check the validity of Michigan neuropathy screening instrument (MNSI) as a screening test and its risk factors for diabetic neuropathy. METHODS: A total of 75 subjects with type II diabetes mellitus, who visited a university hospital, were investigated. We measured their duration of diabetes, height, weight, systolic blood pressure, diastolic blood pressure, fasting glucose, glycosylated hemoglobin, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, serum creatinine, and 24-h urine albumin. MNSI tested and electrophysiological test were performed. RESULTS: The sensitivity, specificity, positive predictive value, and negative predictive value of MNSI was 63.5%, 78.3%, 86.8%, and 48.6%, respectively. Statistically significant relationships were found between neuropathy and the duration of diabetes and total cholesterol. CONCLUSION: MNSI seemed to be an appropriate screening test for diabetic neuropathy. More attention must be paid to the duration of diabetes and the total cholesterol of type 2 diabetic patients with peripheral neuropathy.
