Giant Myofibroblastoma of the Male Breast: A Case Report and Literature Review
- Author:
Kamal Kataria
;
Anurag Srivastava
;
Lavleen Singh
;
Vaishali Suri
;
Rajni Yadav
- Publication Type:Case Reports
- Keywords:
breast, gynecomastia, mesenchymal, myofibroblastoma, spindle cell
- From:Malaysian Journal of Medical Sciences
2012;19(3):74-76
- CountryMalaysia
- Language:English
-
Abstract:
Myofibroblastomas are soft-tissue neoplasms that are thought to arise from myofibroblasts. They are mostly observed in males 41–85 years of age; however, this lesion also occurs in women. The usual clinical presentation is a unilateral painless lump that is not adherent to overlying or underlying structures. Microscopically, myofibroblastomas can be divided into 5 subtypes: classical, epithelioid, collagenised, cellular, and infiltrative. Mammary ducts and lobules are absent in the typical histological subtypes and the adjacent breast parenchyma may form a pseudocapsule. The majority of myofibroblastomas are immunoreactive for CD34, desmin, smooth muscle actin, and vimentin and are negative for cytokeratin and S-100 protein. We present a case of a giant myofibroblastoma arising in the background of gynecomastia in an adult male.
- Full text:W020151027358806433048.pdf
