Radioiodine I-131 For The Therapy Of Graves’ Disease
- Author:
Malik Mumtaz
;
Lim Shueh Lin
;
Khaw Chong Hui
;
Amir Sharifuddin Mohd Khir
- Publication Type:Letter
- Keywords:
radioactive iodine, Graves’ disease, thyroid, treatment, medical sciences
- From:Malaysian Journal of Medical Sciences
2009;16(1):25-33
- CountryMalaysia
- Language:English
-
Abstract:
Graves’ disease is a common cause of hyperthyroidism. Treatment options for Graves’ disease
include antithyroid medication, surgery or radioactive iodine (I-31) or RAI. This review will focus on
the approach to RAI therapy; discussing dose selection, patient preparation, and consideration before
and after administering RAI, examining aspects of pre-treatment with antithyroid medication as well
as discussing possible adverse events including hypothyroidism and possible worsening of thyroidassociated
opthalmopathy. Follow-up is lifelong with the aim of ensuring the patient remains euthyroid
or on replacement therapy if there is evidence of hypothyroidism. While there are controversies
in treatment of thyrotoxicosis with RAI, with appropriate patient selection and regular follow-up,
radioiodine is a safe and effective modality in achieving high cure rates.
- Full text:W020151021602029662432.pdf
