Elevate ALT and AST in an asymptomatic person. What the primary care doctor should do?
- Author:
Loh Keng Yin
;
Kew Siang Tong
- Publication Type:Journal Article
- From:Malaysian Family Physician
2009;4(2 & 3):98-99
- CountryMalaysia
- Language:English
-
Abstract:
ABSTRACT
• Abnormal liver function test with raised alanine aminotransferase (ALT) and raised aspartate aminotransferase (AST) are commonly seen in primary care setting.
• Chronic alcohol consumption, drugs, non-alcoholic steatohepatitis (NASH) and chronic viral hepatitis are common causes associated with raised ALT and AST.
• In chronic viral hepatitis, the elevation of liver enzyme may not correlate well with the degree of liver damage.
• Non-hepatic causes of raised ALT and AST include polymyositis, acute muscles injury, acute myocardial infarction and hypothyroidism.
• In the primary care setting, the doctor should obtain a complete history regarding the risk factors for viral hepatitis, substance abuse and request investigations accordingly.
• Suspected chronic viral hepatitis and liver cirrhosis are best referred to hepatologist for further management.
- Full text:W020151007365681363361.pdf
