Risk Determinants of Peripheral Neuropathy in Patients with Type II Diabetes Mellitus Attending Follow-Up Clinics at Universiti Kebangsaan Malaysia Medical Center (UKMMC): A Cross-Sectional Study
- Author:
Fatimah AB
;
Aziz NA
;
Amaramalar SN
;
Aznida FAA
;
Hamid MZA
;
Norlaila M
- Publication Type:Journal Article
- Keywords:
diabetes mellitus, peripheral neuropathy, Neuropathy Disability Score (NDS), Semmes Weinstein monofilament (SWMF), callus
- From:Medicine and Health
2010;5(1):34-40
- CountryMalaysia
- Language:English
-
Abstract:
Peripheral neuropathy is highly associated with foot complications among diabetics. This study aimed to identify risk factors associated with the development of peripheral neuropathy in diabetic patients and their association with degree of severity of peripheral neuropathy. A cross-sectional study was conducted in follow-up clinics at the Universiti Kebangsaan
Malaysia Medical Centre (UKMMC), Malaysia involving 72 diabetic patients and 19 controls. Exclusion criteria were those with amputated limbs, gross foot deformity
and existing peripheral neuropathy. Controls were non diabetics who walked normally, had no history of foot problem and attended the clinic as subjects’ companion. Quantitative assessment of neuropathy was done using Semmes-Weinstein monofilament. Neuropathy
Disability Score (NDS) were used to quantify severity of diabetic neuropathy. Spearman’s Rank test and Mann-Whitney test were used to determine correlation between
variables and their differences. Logistic regression analysis was used to determine risk factors associated with peripheral neuropathy. The mean HbA1c among diabetics
was 8.6% + 4.1, and mean NDS was 7.0 + 6.0. A total of 79.1% demonstrated various level of neuropathy with presence of callus was associated with higher NDS
scores. Older age (P=0.02), body weight (P=0.03), HbA1c (P=0.005) and duration of diabetes (P <0.005) showed positive correlation with NDS. Proper foot care program for
diabetics should include recognition of the callus, with special emphasis given to those with heavier weight and increasing age.
- Full text:P020160928394629370903.pdf
