Acute Generalized Exanthematous Pustulosis Caused by Daptomycin.
10.5021/ad.2011.23.S3.S288
- Author:
Teoh Yee LENG
1
;
Mark Koh Jean AAN
;
Michelle CHAN
;
Liu Tsun TSIEN
Author Information
1. Department of Dermatology, Changi General Hospital, Singapore 529889, Singapore. docmark@pacific.net.sg
- Publication Type:Case Report
- Keywords:
Acute generalized exanthematous pustulosis;
Daptomycin
- MeSH:
Acute Generalized Exanthematous Pustulosis;
Anti-Bacterial Agents;
Daptomycin;
Gram-Positive Bacteria;
Methicillin-Resistant Staphylococcus aureus;
Skin;
Soft Tissue Infections;
Vancomycin
- From:Annals of Dermatology
2011;23(Suppl 3):S288-S289
- CountryRepublic of Korea
- Language:English
-
Abstract:
Daptomycin, a lipopeptide antibiotic with similar action as vancomycin, is used to treat complicated skin and soft tissue infections caused by resistant Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, penicillin-resistant streptococci, and vancomycin-resistant enterococci. Acute generalized exanthematous pustulosis (AGEP), characterized by acute onset of numerous sterile, nonfollicular pinhead sized pustules, is common secondary to drugs, in particular, antibiotics. We present the first case of AGEP following the use of daptomycin.