Soybean, Cassava And Cabbage Locally Grown In A Iodine Deficient Area In Central Java Are Goitrogenic To Rats
- Author:
Yulia Lanti Retno Dewi
;
Widardo
;
Bambang Suprapto
- Publication Type:Journal Article
- Keywords:
goitrogen;
soybean;
cassava;
cabbage
- From:Malaysian Journal of Public Health Medicine
2017;17(1):78-83
- CountryMalaysia
- Language:English
-
Abstract:
Although the relation of iodine deficiency to endemic goiter is well established, other factors may be involved. Some
factors are related to food. The aim of the study was to prove that some foods locally grown in an iodine deficient area
are goitrogenic. Twenty eight Wistar rats age 28 days, weight 60-70 g were randomly assigned into seven groups. The
first group fed with AIN-93G as control group. Group II and III were given 25% and 50% raw soybean replacing the same
weight of AIN-93G. Group IV and V were given 25% and 50% raw cassava replacing the same weight of AIN-93G. Group VI
and VII were given 25% % and 50% raw cabbage replacing the same weight of AIN-93G. The length of the experiment was
34 days. The results showed that the control group fed with AIN-93G grew optimally, while the other groups showed
deficits in growth significantly. Histological preparation of the thyroid gland were carried out under hematoxilyn eosin
staining. Both 25% and 50% of raw soybean, raw cassava and raw cabbage produced colloid goiter. The study proved that
foods locally grown in an iodine deficient area are goitrogenic.
- Full text:P020170622464790137484.pdf
