Prevalence Of Metabolic Syndrome And Its Associated Factors In Patients With Major Depressive Disorder (MDD)
- Author:
Chawanun Charnsil
;
Sudrak Pilakanta
;
Suksiri Panikul
- Publication Type:Journal Article
- Keywords:
Depression;
Metabolic Syndrome;
Prevalence
- From:ASEAN Journal of Psychiatry
2015;16(2):1-5
- CountryMalaysia
- Language:English
-
Abstract:
To determine the prevalence of metabolic syndrome and examine its
association with patients with major depressive disorder. Methods: All patients
diagnosed with major depressive disorder (MDD) who visited the Psychiatric
Outpatient Clinic at Maharaj Nakorn Chiang Mai Hospital were invited to
participate in this study. Subjects who met the inclusion criteria and did not
have exclusion criteria were included in this project until 140 subjects were
enrolled. The criteria proposed by the American Heart Association/National
Heart, Lung, and Blood Institute (updated ATPIII) were utilized for diagnosing
metabolic syndrome. Age, history of antidepressant and antipsychotic use, time
of illness, severity of illness and family history of metabolic syndrome were
assessed as factors associated with metabolic syndrome. Data was analyzed by
using percentage, mean, standard deviations, student t-test, chi-square test and
Fisher’s exact test. Results: One hundred forty subjects were recruited. The
prevalence of metabolic syndrome determined by the American Heart
Association/National Heart, Lung, and Blood Institute (updated ATPIII) was
37.9% (53). Age was significantly associated with metabolic syndrome in patients
with a major depressive disorder (p≤0.001). The duration of illness, duration of
treatment, family history of diabetes, hypertension and dyslipidemia were not
associated with metabolic syndrome. Conclusions: A high proportion of Thai
patients with MDD had metabolic syndrome. These findings support the
importance of assessing and monitoring metabolic syndrome in MDD patients,
especially in older patients.
- Full text:P020150727418136158876.pdf
