Thin At What Cost? Case Reports Of Sibutramine-Induced Psychotic Disorders
- Author:
Sutapa Basu
;
Swapna Verma
- Publication Type:Case Reports
- Keywords:
Sibutramine;
First Episode;
Psychoses
- From:ASEAN Journal of Psychiatry
2014;15(2):213-216
- CountryMalaysia
- Language:English
-
Abstract:
Objective: The objective of these 4 case reports is to highlight that psychotic
symptom can occur due to the consumption of sibutramine. The psychosis is
usually self-remitting, once its consumption is stopped. Methods: All cases with
first episode psychosis presenting to a tertiary mental health Institute in
Singapore were screened and 4 consecutive sibutramine-induced psychoses cases
are reported. Results: All the 4 cases that were diagnosed with Sibutramine
induced psychoses, had history of consumption of the substance in the tablet
form or in substances like slimming tea or slimming powders. In 2 out of the 4
cases, no antipsychotics were started. In the 2 cases that received antipsychotics,
they were for short duration. There was a temporal association between the
consumption of sibutramine containing substances and the onset of psychotic
symptoms. All patients were on follow up for two years and in 2 patients, there
were no recurrence of psychotic symptoms. In 2 patient recurrent psychotic
symptoms were temporally related with consumption of sibutramine and
symptoms remitted when the consumption was stopped. Conclusions: Despite
sibutramine being banned in several countries, it can still be purchased from
countries allowing its sale and from online stores. Labeling a patient having
schizophrenia can be avoided if detailed history, specifically enquiring about the
consumption of sibutramine is obtained.
- Full text:P020150205461042927380.pdf
