Neonatal lupus erythematosus presenting as multiple photosensitive annular plaques with skin atrophy
- Author:
Sabeera BKI
;
Mardziah A
- Publication Type:Case Reports
- Keywords:
congenital skin anomaly, skin ulceration, skin atrophy
- From:Malaysian Journal of Dermatology
2012;28(-):30-33
- CountryMalaysia
- Language:English
-
Abstract:
Neonatal lupus erythematosus (NLE) is an
autoimmune disease affecting the fetus as a
result of transplacental transfer of anti-Ro
autoantibodies. Typically, it presents in the first
few months of life with an annular form of
subacute cutaneous lupus erythematosus. We
report an infant of NLE presenting at birth with
multiple annular erythematous plaques with skin
atrophy involving the face, head, and upper trunk.
Histopathology of skin biopsy was consistent
with subacute cutaneous lupus. The mother was
clinically free of disease and had no family
history of autoimmune disease. Serology (extranuclear
antigens) was positive in both the baby
and the mother. This is a rare presentation of a
rare disease.
