Disseminated fusariosis in a patient with acute lymphoblastic leukaemia: A case report and literature review
- Author:
Tang Jyh Jong
- Publication Type:Case Reports
- Keywords:
disseminated fusariosis, acute Lymphoblastic Leukaemia, fusarium spp, deep fungal infection
- From:Malaysian Journal of Dermatology
2012;28(-):18-21
- CountryMalaysia
- Language:English
-
Abstract:
Fusarium spp are molds found in the soil and
may be saprophytic or fa c u l t a t ive plant
p a t h ogens. These are rare but important
opportunistic pathogens in immunocompromised
patients especially those with hematologic
malignancies. Fusarium spp usually cause local
infections such as onychomycosis and infections
of surgical and burn wound. However more
importantly, these pathogens can lead to severe
disseminated infection with invo l vement of
multiple organs including skin. This disseminated
form of fusariosis occurs exclusively in patients
with prolonged, severe neutropaenia especially in
patients with acute leukaemia or those
u n d e rgoing bone marrow transplantation.
Prognosis of disseminated fusariosis is usually
guarded if not recognized early. We report a rare
case of disseminated fusariosis in a patient with
acute lymphoblastic leukaemia.
