Prevalence, antibiogram profile and cross transmission of Pseudomonas aeruginosa in a tertiary burn unit
- Author:
Emmanuel Maundy Ikpeme
;
Kingsley Hovana Enyi-Idoh
;
Joseph Fuh Nfongeh
;
Lawrence Bassey Etim
;
Felix Chinedu Akubuenyi
- Publication Type:Letter
- Keywords:
Nosocomial infection, drug susceptibility, cross transmission
- From:Malaysian Journal of Microbiology
2013;9(1):116-119
- CountryMalaysia
- Language:English
-
Abstract:
Aims: Pseudomonas aeruginosa is an opportunistic pathogen that still develops life threatening infections in patients
with immunological system defects like burns. The major problem with this organism is the ability to persist during
infections due to its high rate of resistance to many drugs. This study was designed to evaluate the prevalence and drug susceptibility profile of Pseudomonas aeruginosa in patients admitted to a burn unit in a tertiary health facility.
Methodology and Result: From 80 selected patients, appropriate clinical specimens from burn sites were collected and processed for the isolation and identification of Pseudomonas aeruginosa.. Also, 78 surveillance samples from various
environmental sites and hands impressions of nursing staff in the burn unit were cultured for the isolation of
Pseudomonas aeruginosa. Drug susceptibility profile showed high resistance for ceftazidime (40.7%) ciprofloxacin
(13.1%) and piperacillin (34.6%); furthermore, low resistance for some antibiotics like imipenem (17.5%)
pipereracillin/tazobactam (12.3%) and aztreonam (16%) were obtained. In addition, 8 multiresistant Pseudomonas
aeruginosa (MRPA) isolates were recovered from clinical specimens and from environmental samples.
Conclusion, significance and impact of study: Evidence of high prevalence of clinical and environmental MRPA
reported in this study provides the rationale for strict enforcement of infection prevention protocol to minimize cross transmission of bacterial pathogens in hospital burn units and consequent disease burden arising from MRPA.
- Full text:P020160926365405195469.pdf
