D-penicillamine - induced pemphigus in a patient with Wilson disease
- Author:
Loh LC
;
Goh KL
;
Rosnah Zain
- Publication Type:Case Reports
- From:Malaysian Journal of Dermatology
2008;21(-):87-89
- CountryMalaysia
- Language:English
-
Abstract:
Pemphigus is an autoimmune blistering disease characterized by circulating autoantibodies directed against the keratinocyte cell surface.
Majority of patients with pemphigus develop the disease
spontaneously. However, there is a small group of patients who develop pemphigus after treatment with certain medications, of which Dpenicillamine
(DPA) and captopril are the best documented. We report
a case of DPA-induced pemphigus vulgaris in a young Chinese lady treated with DPA for Wilson disease.