Erythroderma - A retrospective study with special emphasis on good prognosis
- Author:
Peter Ch’ng WB
;
Adam B
;
Rohna R
- Publication Type:Journal Article
- Keywords:
exfoliative dermatitis, generalised erythema, outcome
- From:Malaysian Journal of Dermatology
2011;26(-):1-5
- CountryMalaysia
- Language:English
-
Abstract:
Background Erythroderma is a serious condition in itself, quite apart from hazards associated with
the underlying disease, and is sometimes fatal. Prognostic studies are rare in the literature and to date
there are no published studies to identify the factors that can determine good prognosis.
Objectives The aim of the study is to determine the factors that can prognosticate the good outcome
of erythroderma.
Methodology Cross sectional study from patients diagnosed to have erythroderma between 2003
and 2007 were analyzed with regard to age, sex, race, underlying medical illness, aetiology, duration
of rash before diagnosis of erythroderma, response to topical therapy and prognosis.
Results Four variables (aetiology, gender, duration of rash before being diagnosed as erythroderma
and response to topical therapy) were associated with good prognosis. These variables were
statistically significant from univariate analysis. When these variables were included into the binary
logistic model, the study did not have enough evidence to proof that ‘aetiology’ and ‘gender’ can
determine good prognosis. Response to topical therapy and shorter duration of rash (equal and less
than 120 days) were significant with odds ratio (CI) of 4.11 (1.556, 10.885) and 4.608 (1.903,
11.155) respectively.
Conclusion Shorter duration of rash and response to topical therapy are important factors to
determine a good prognosis.
