The Efficacy of Flavonoid Antioxidant from Chocolate Bean Extract: Prevention of Myocyte Damage Caused by Reperfusion Injury in Predominantly Anaerobic Sports
- Author:
HN Rasyid
;
YD Ismiarto
;
R Prasetia
- Publication Type:Journal Article
- Keywords:
Chocolate bean extract, Flavonoid, Malondialdehyde
- From:Malaysian Orthopaedic Journal
2012;6(2):3-6
- CountryMalaysia
- Language:English
-
Abstract:
Background: Use of predominantly anaerobic energy
systems such as that seen in 800-meter athlete runners
disrupts mitochondrial function as an energy source.
Furthermore, it produces free radical substances and causes
myocyte damage. Malondialdehyde (MDA) plasma
concentrations correlate with free radical levels and are
therefore predictive of cell damage. Objective: To analyse
the effect of flavonoid antioxidant from chocolate bean
extract for prevention of lipid peroxidation of myocyte
membranes caused by free radical substances in athletes
partaking in predominantly anaerobic sports. Materials and
Methods: The study of population consisted of 16 junior
athletes who compete in 800-meter races. This was a
randomized experimental study. Subjects were divided into
two groups, chocolate bean extracts and placebo groups, and
then practiced regularly for 14 days. All subjects were
assessed on day 15. Results were analysed statistically using paired t test, ANOVA and Duncan tests. Results:
Concentrations of MDA were reduced in flavonoid group.
Conclusion: Flavonoid antioxidant from chocolate bean
extract may prevent myocyte damage was caused by
reperfusion injury.
- Full text:W020160108415185906317.pdf
